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. 2022 Mar 30;17(1):2014677. doi: 10.1080/15592324.2021.2014677

Figure 1.

Figure 1.

Possible work model for lncRNAs recruit chromatin modifiers. A. histone modifiers bind lncRNA directly. B. lncRNAs is found by a bridge protein (such as RNA-binding protein), which interacts with chromatin modifiers, then they form a super-complex maintain local chromatin landscape. C. Stress condition (as cold) prompt lncRNAs and chromatin modifiers form phase separation system, then they can easily maintain local chromatin landscape.