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. 2022 Mar 18;9:870680. doi: 10.3389/fnut.2022.870680

Figure 5.

Figure 5

The expression pattern of genes involved in the cholesterol transformation pathway. (A) GSEA plots depicting the enrichment of genes in the cholesterol transformation pathway of livers from PEDV-infected piglets compared to the controls. FDR, false-discovery rate. (B) Heatmap of mRNA expression (RNA-seq) changes of the genes involved in cholesterol transformation to bile acids in the livers of PEDV-infected piglets (log2 transformed, normalized to Control). (C) The qRT-PCR analysis confirmed expression changes of genes in the cholesterol transformation pathway in the livers of PEDV-infected piglets. The data are shown as the means ± SEM, *P < 0.05, ***P < 0.001, using the two-tailed Student t-test.