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Efficacy of FK463 in mouse models of pulmonary fungal infection
| A. fumigatus strain | Inoculum (105 CFU) | ED50 (mg/kg/day)a of:
|
|
|---|---|---|---|
| FK463 | AMPH-B | ||
| TIMM0063 | 8.8 | 0.35 (0.24–0.51) | 0.36 (0.24–0.52) |
| IFM40814 | 7.0 | 0.26 (0.18–0.36) | 0.26 (0.18–0.36) |
| IFM41209 | 3.5 | 0.51 (0.34–0.75) | 0.46 (0.32–0.67) |
Values in parentheses are 95% confidence intervals.
