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. 2022 Feb 22;13(2):4260–4270. doi: 10.1080/21655979.2022.2031388

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Effects of Tan IIA on Ang II–induced hypertrophy of H9c2 cells. (a) Molecular structure of Tan IIA. (b) MTT assay was performed to measure the inhibition rate of Tan IIA on the H9c2 cells. (c) Immunofluorescence staining of α-actin was performed to evaluate the surface area of H9c2 cells. (d, e) qPCR and Western blot were used to detect the expression of ANP, BNP, and β-MHC. ***P < 0.001 vs. control group, ^#P < 0.05 vs. Ang II group, ^##P < 0.01 vs. Ang II group, ^###P < 0.001 vs. Ang II group.