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miR-665-3p antagomir reduces HFD-induced hepatic oxidative stress and inflammation. (a) Hepatic ROS levels determined by DCFH-DA probe. (b) H2O2 levels in the liver. (c) MDA levels in the liver. (d-e) Hepatic IL-1β, IL-6, MCP-1, TNF-α and IL-10 levels determined by the commercial ELISA kits. All results were expressed as the means ± standard deviations, n = 6 for each group, and *P < 0.05 was considered statistically significant.
