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. 2022 Jan 26;13(2):3810–3826. doi: 10.1080/21655979.2022.2031420

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — miR-656-3p regulates CRC cell migration and chemotherapy resistance through the SGPP1. (a) Venn diagram analyzed the potential target genes of miR-656-3p in three databases. (b–e) Correlation analysis of miR-656-3p abundance and the mRNA of SGPP1, RORA, ITGB8, and RGCC, respectively. (f–g) WB of SGPP1 protein expression in miR-656-3p knockdown SW480 cells and miR-656-3p overexpressed DLD1 cells. (h) qRT-PCR analysis of SGPP1 protein expression in miR-656-3p knockdown SW480 cells and miR-656-3p overexpressed DLD1 cells. ***p < 0.001 compared with group LV-mNC.