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. 2022 Feb 24;13(3):6208–6221. doi: 10.1080/21655979.2022.2037249

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Highly expressed miR-23a-3p was found in cholangiocarcinoma tissues as well as cells. (a) Heatmap of primary 50 differential expressed miRNAs in 36 cholangiocarcinoma tissues in comparison to 9 adjacent tissues. (b) MiR-23a-3p was overexpressed confirmed by qRT-PCR in 60 pairs of cholangiocarcinoma tissues as well as normal tissues. (c) Higher miR-23a-3p level was observed in 4 cholangiocarcinoma cell lines (QBC939, HUCCT1, RBE, HCCC9810) compared to normal cell line HiBEC. (d) QRT-PCR detected the transfection efficacy after transfection with miR-23a-3p inhibitor or inhibitor NC in HUCCT1. (e) QRT-PCR detected the transfection efficacy after transfection with miR-23a-3p mimics as well as mimics NC in RBE.