Figure 4.

Decreasing miR-23a-3p expression could inhibit growth, as well as metastasis of tumor in vivo. (a) The image of tumor in miR-23a-3p inhibitor as well as inhibitor NC groups. (b) The tumor growth curve when miR-23a-3p been knockdown. (c) The average tumor weight when miR-23a-3p been knockdown. (d) HE staining of subcutaneous tumors. (e) Detected PanCK protein using IHC staining of subcutaneous tumors. (f) Down-regulation of Ki-67 in miR-23a-3p inhibitor group in comparison to inhibitor NC group. (g-i) Lung metastasis and HE staining results of tumor when miR-23a-3p been knockdown.