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. 2022 Feb 24;13(3):6208–6221. doi: 10.1080/21655979.2022.2037249

Table 2.

Correlation of miR-23a-3p expression with clinicopathological characteristics in CCA patients

Parameters Total ICCA
P-value Parameters Total ECCA
Total
High level Low level High level Low level
Age         Age        
<60 17 7 10 0.328 <60 15 8 7 0.647
≥60 21 12 9 ≥60 7 3 4
Gender         Gender        
Male 21 11 10 0.744 Male 17 9 8 0.611
Female 17 8 9 Female 5 2 3
Tumor numbers         Tumor numbers        
1 32 15 17 0.374 1 19 9 10 0.534
≥1 6 4 2 ≥1 3 2 1
Tumor size(cm)         Tumor size(cm)        
<5 13 3 10 0.017* <3 19 9 10 0.534
≥5 25 16 9 ≥3 3 2 1
Pathologic grade         Pathologic grade        
I+ II 12 7 5 0.485 I+ II 9 5 4 0.665
III+IV 26 12 14 III+IV 13 6 7
Vascular invasion         Vascular invasion        
yes 27 13 14 0.721 yes 12 5 7 0.392
no 11 6 5 no 10 6 4
Perineural invasion         Perineural
invasion
       
yes 25 15 10 0.087 yes 15 8 7 0.647
no 13 4 9 no 7 3 4
Lymph node metastasis         Lymph node metastasis        
yes 15 11 4 0.020* yes 4 4 0 0.027*
no 23 8 15 no 18 7 11
TNM stage         TNM stage        
I+ II 18 10 8 0.516 I+ II 6 2 4  
III+IV 20 9 11 III+IV 16 9 7 0.338