Table 1.
Centriolar/centrosomal genes expression (microarray)
| Gene | Lung cancer patients | |||
|---|---|---|---|---|
| Tumor (n = 163) | Paired non-malignant (n = 163) | Ratio (T/N) | p-value | |
| STIL/MCPH7 | 137.8 | 39.5 | 3.5 | 1.8E−29 |
| SASS6 | 122.5 | 75.3 | 1.6 | 1.0E−19 |
| SPICE1 | 184.1 | 116.7 | 1.5 | 1.1E−18 |
| PLK4 | 57.8 | 37.7 | 1.5 | 2.3E−22 |
| CEP295/KIAA1731 | 73.1 | 53.5 | 1.3 | 5.7E−08 |
| POC5 | 212.4 | 164.4 | 1.2 | 3.6E−08 |
| CEP152/MCPH9 | 27.4 | 24.1 | 1.1 | 8.1E−08 |
| CPAP/CENPJ/MCPH6 | 111.7 | 104.6 | 1.0 | 4.3E−03 |
| CETN1 | 27.3 | 26.6 | 1.0 | 8.8E−02 |
| RTTN | 141.7 | 139.4 | 1.0 | 1.9E−03 |
| CEP135/MCPH8 | 81.7 | 81.6 | 1.0 | 5.6E−02 |
| CEP63 | 128.9 | 144.0 | 0.9 | 1.3E−01 |
| POC1B | 376.0 | 425.2 | 0.9 | 3.8E−03 |
| CEP120 | 401.9 | 507.8 | 0.8 | 3.1E−11 |
The microarray data of 163 paired lung cancer patients and their adjacent non-malignant lung tissues were derived from GEO
Ranking is based on the ratio between tumor (T) and paired non-malignant lung specimens (N)
Significance is determined by paired t-test