Table 1.
Characteristics | No-Chemotherapy (n = 2574) | Chemotherapy (n = 2122) | Total (n = 4696) | Pc | ||||
---|---|---|---|---|---|---|---|---|
No | % | No | % | No | % | |||
Median follow-up (months) (IQR) | 27(12–49) | 27(12–47) | 27(12–48) | |||||
Age (years) | 70–79 | 1257 | 48.8 | 1836 | 86.5 | 3093 | 65.9 | < 0.001 |
80 + | 1317 | 51.2 | 286 | 13.5 | 1603 | 34.1 | ||
Race | White | 2003 | 77.8 | 1636 | 77.1 | 3639 | 77.5 | 0.238 |
Black | 383 | 14.9 | 348 | 16.4 | 731 | 15.6 | ||
Othera | 188 | 7.3 | 138 | 6.5 | 326 | 6.9 | ||
Marital status | Married | 959 | 37.3 | 1085 | 51.1 | 2044 | 43.5 | < 0.001 |
Not marriedb | 1615 | 62.7 | 1037 | 48.9 | 2652 | 56.5 | ||
Grade | I and II | 707 | 27.5 | 388 | 18.3 | 1095 | 23.3 | < 0.001 |
III | 1867 | 72.5 | 1734 | 81,7 | 3601 | 76.7 | ||
AJCC stage | I | 1317 | 51.2 | 706 | 33.3 | 2023 | 43.1 | < 0.001 |
II | 960 | 37.3 | 999 | 47.1 | 1959 | 41.7 | ||
III | 297 | 11.5 | 417 | 8.9 | 714 | 15.2 | ||
Tumor status | T1 | 1435 | 55.7 | 910 | 42.9 | 2345 | 49.9 | < 0.001 |
T2 | 876 | 34.0 | 919 | 43.3 | 1795 | 38.2 | ||
T3 | 150 | 5.8 | 148 | 7.0 | 298 | 6.3 | ||
T4 | 113 | 4.4 | 145 | 6.8 | 258 | 5.5 | ||
Nodal status | N0 | 2039 | 79.2 | 1290 | 60.8 | 3329 | 70.9 | < 0.001 |
N1 | 357 | 13.9 | 556 | 26.2 | 913 | 19.4 | ||
N2 | 104 | 4.0 | 172 | 8.1 | 276 | 5.9 | ||
N3 | 74 | 2.9 | 104 | 4.9 | 178 | 3.8 | ||
Surgery approach | No surgery | 150 | 5.8 | 107 | 5.0 | 257 | 5.5 | 0.239 |
Mastectomy and BCS | 2424 | 94.2 | 2015 | 95.0 | 4439 | 94.5 | ||
Radiation status | Yes | 1013 | 39.4 | 1179 | 55.6 | 2192 | 46.7 | < 0.001 |
No | 1561 | 60.6 | 943 | 44.4 | 2504 | 53.3 |
Abbreviation: AJCC American Joint Committee on Cancer, BCS Breast-conserving surgery, IQR Interquartile range
aOther includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown
bNot married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
cThe P value of the Chi-square test was calculated between the chemotherapy and no-chemotherapy groups, and bold type indicates significance