Table 2.
Multivariate Cox proportional hazard model of breast cancer-specific survival (BCSS) and overall survival (OS) in all patients
| Variables | BCSS | OS | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age (years) | 70–79 | Reference | Reference | ||
| 80 + | 1.315(1.111–1.557) | 0.001 | 1.629(1.429–1.856) | < 0.001 | |
| Marital status | Married | Reference | Reference | ||
| Not marrieda | 1.062(0.902–1.250) | 0.472 | 1.120 (0.985–1.272) | 0.084 | |
| Race | White | Reference | Reference | ||
| Black | 1.068 (0.875–1.305) | 0.516 | 1.070 (0.914–1.252) | 0.399 | |
| Otherb | 0.706 (0.507–0.983) | 0.039 | 0.709 (0.549–0.916) | 0.008 | |
| Grade | I and II | Reference | Reference | ||
| III | 1.510 (1.222–1.865) | < 0.001 | 1.344(1.152–1.568) | < 0.001 | |
| Stage | I | Reference | Reference | ||
| II | 3.982 (3.137–5.055) | < 0.001 | 2.602(2.221–3.048) | < 0.001 | |
| III | 11.609(9.015–14.949) | < 0.001 | 6.528(5.468–7.793) | < 0.001 | |
| Surgery approach | No surgery | Reference | Reference | ||
| Mastectomy and BCS | 0.246(0.198–0.304) | < 0.001 | 0.293(0.245–0.351) | < 0.001 | |
| Radiation | No | Reference | Reference | ||
| Yes | 0.626 (0.529–0.741) | < 0.001 | 0.565 (0.495–0.645) | < 0.001 | |
| Chemotherapy | No | Reference | Reference | ||
| Yes | 0.656 (0.553–0.779) | < 0.001 | 0.561(0.488–0.644) | < 0.001 | |
Abbreviation: 70–79 70–79 years old, 80 + More than 80 years old, BCS Breast Conserving Surgery, HR Hazard ratio
aNot married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
bOther includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown. Bold type indicates significance