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. 2022 Feb 27;13(3):6500–6508. doi: 10.1080/21655979.2022.2033013

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — PB2 inhibited viability and promoted apoptosis of OSCC cells. (a) The chemical structure of PB2. (b) The viability of oral mucosa epithelial cell (OMEC) treated with PB2 was detected by CCK-8 assay. (c) The viability of human OSCC cell line (SCC-25) treated with PB2 was detected by CCK-8 assay. (d) The apoptosis of SCC-25 cells treated with PB2 was analyzed by Tunel assay. (e) The expression of apoptosis related proteins in SCC-25 cells treated with PB2 was determined by Western blot. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. PB2 (0 μM) group.