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. 2022 Jan 30;13(2):3450–3461. doi: 10.1080/21655979.2021.2024685

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — TB-II inhibited the production of oxidant markers in IL-1β-treated SW1353 cells and chondrocytes. The mRNA expression of (a) iNOS and (b) COX-2 were detected by qRT-PCR. (c, d) The protein level of iNOS and COX-2 was detected by Western blot and quantified. GAPDH was conducted as a loading control. The levels of (e) NO and (f) PGE2 were determined using ELISA. One-way ANOVA, ##p < 0.01, compared with control cells; ^$p < 0.05, ^$$p < 0.01, ns: not-significant, compared with IL-1β-treated cells.