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Effect of CYLD on chromatin accessibility and H3 modification. (A) Chromatin accessibility assay of mCyld+/+ and mCyld−/− cell lines. Quantification of relative chromatin accessibility to mCyld−/− cells. (B) H3 modification assay of mCyld+/+ and mCyld−/− cell lines (normalized to total amount of H3). n=2. *P<0.05. CYLD, CYLD lysine 63 deubiquitinase; H3, histone 3.
