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. 2022 Feb 13;13(3):4832–4843. doi: 10.1080/21655979.2022.2034586

Figure 6.

Figure 6.

miR-656-3p impedes melanoma cell viability, migration, and invasion via SERBP1

(A and B) RT-qPCR and Western blotting showed SERBP1 level in A375 cells transfected with NC mimics, miR-656-3p mimics, pcDNA3.1, SERBP1, and miR-656-3p mimics + SERBP1.(C and D) CCK-8 and colony formation experiments showed cell viability in A375 cells transfected with NC mimics, miR-656-3p mimics, pcDNA3.1, SERBP1, and miR-656-3p mimics + SERBP1.(E) Wound healing assay showed cell migration in A375 cells transfected with NC mimics, miR-656-3p mimics, pcDNA3.1, SERBP1, and miR-656-3p mimics + SERBP1.(F) Matrigel assay showed the invasion ability of A375 cells transfected with NC mimics, miR-656-3p mimics, pcDNA3.1, SERBP1, and miR-656-3p mimics + SERBP1.*P < 0.05; **P < 0.01.