Table 1.
The difference in clinical data of the study population
| Features | Healthy controls (n = 68) |
AS patients (n = 137) |
P value |
| Age (years) | 48.95 ± 4.49 | 49.07 ± 4.38 | 0.850 |
| Sex (male/female) | 37/31 | 75/62 | 0.964 |
| BMI (kg/m2) | 22.16 ± 2.83 | 22.87 ± 3.37 | 0.117 |
| TC (mmol/L) | 4.03 ± 0.80 | 4.24 ± 1.09 | 0.153 |
| HDL-C (mmol/L) | 1.59 ± 0.56 | 1.63 ± 0.50 | 0.647 |
| LDL-C (mmol/L) | 2.86 ± 0.85 | 3.12 ± 0.83 | 0.042 |
| TG (mmol/L) | 1.36 ± 0.086 | 1.38 ± 0.077 | 0.089 |
| FBG (mmol/L) | 4.95 ± 0.50 | 4.93 ± 0.59 | 0.785 |
| ALT (U/L) | 18.35 ± 8.72 | 20.21 ± 10.14 | 0.175 |
| AST(U/L) | 19.79 ± 10.16 | 21.08 ± 10.55 | 0.398 |
| UA (mm Hg) | 247.85 ± 64.04 | 251.44 ± 65.62 | 0.708 |
| Cre (mm Hg) | 69.83 ± 21.36 | 70.94 ± 19.15 | 0.718 |
| Hcy (μmol/L) | 10.67 ± 2.45 | 11.46 ± 2.35 | 0.030 |
| CRP (mg/l) | 6.13 ± 1.89 | 19.56 ± 3.22 | <0.001 |
Note: TC: Total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG: triglyceride; FBG, fasting blood glucose; ALT, alanine aminotransferase; AST, aspartate aminotransferase; UA, uric acid; Cre, serum creatinine; Hcy, homocysteine; CRP, C-reactive protein.