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. 2022 Jan 16;13(2):2308–2320. doi: 10.1080/21655979.2021.2024396

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — TRIM28 promotes prostate cancer tumorgenesis in vitro and in vivo. A. RT-qPCR analysis assessing UBXN10-AS expression was detected in COAD cells and FHC cells. *P < 0.05,**P < 0.001 vs. FHC. B. RT-qPCR analysis assessing UBXN10-AS expression was detected in COAD tissue and normal tissues. **P < 0.001. C. Subcellular localization of UBXN10-AS1 in SW480 and SW620 cells. D. UBXN10-AS expression in SW480 and SW620 cells infected with Lv-UBXN10-AS and Lv-NC by RT-qPCR. E. CCK8 assay determining the proliferation of cells in (D). F. Wound healing assay assessing the migration of cells in (D). G. UBXN10-AS1 overexpression inhibits in vivo tumor growth. The tumor volume and weight were significantly lower in the UBXN10-AS-overepxression group than those in the NC group. (D-G) Empty vector, empty lentivirus vectors. UBXN10-AS1-OE, UBXN10-AS1-overexpressing lentivirus vectors. **P < 0.001 vs. empty vectors.