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. 2022 Jan 16;13(2):2308–2320. doi: 10.1080/21655979.2021.2024396

Figure 6.

Figure 6.

SLIT3 overexpression offsets the pro-tumorigenic role of miR-515-5p overexpression in COAD. A. The expression changes of SLIT3 protein were assessed by Western blots. B. CCK8 assays detected the proliferation capacity of indicated SW480 and SW620 cells. C. scratch wound-healing migration assays detected the migration capacity of indicated SW480 and SW620 cells. Empty vector, pcDNA 3.1 empty vectors. SLIT3-OE, SLIT3 overexpression vectors. mimic, miR-515-5p mimic. *P < 0.001, **P < 0.001 vs. Empty vector; &P < 0.05, &&P < 0.001 vs. mimic-NC; #P < 0.05, ##P < 0.001 vs. SLIT3-OE+mimic.