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. 2022 Feb 22;13(3):6012–6023. doi: 10.1080/21655979.2022.2042133

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Elevated FOXD3-AS1 was observed in GBM and is correlated with poor prognosis.

(A) According to the TCGA dataset, FOXD3-AS1 expression was upregulated in GBM patient tissue samples (*p < 0.05). (B) According to the TCGA dataset, level of FOXD3-AS1 was remarkably higher in higher WHO grade of GBM patient. (*p < 0.05) (C) qRT-PCR results showed that FOXD3-AS1 expression was increased in different GBM cell lines compared to normal NHA cells (N = 3, *p < 0.05). (D) Kaplan–Meier analysis indicated that a higher level of FOXD3-AS1 indicated worse prognosis for GBM patients.