Figure 2.

Smurf1 silencing inhibits oxidative stress levels and improves cardiac function in CHF rats. A: Smurf1 expression in myocardial tissue of rats detected by qRT-PCR and WB; B: Cardiac function indexes after modeling were detected by echocardiography; C: The ratios of heart weight/body weight, left ventricle weight/body weight, and lung weight/body weight were measured; D: Histopathological changes of the myocardium observed by HE staining; E: Masson staining observed the degree of myocardial tissue fibrosis; F: The levels of SOD, GSH-Px and MDA detected by ELISA; N = 10; Values in the figure were measurement data, which were displayed as mean ± standard deviation. Unpaired t test was used for comparisons. * P < 0.05.