Figure 1.

Circ_0068464 expressions in colorectal cancer tissues and cells. (a) GEO database and the intersection of DNA arrays were utilized to explore CRC-related circRNA; (b–c) QRT-PCR was applied to determine circ_0068464 expression in CRC tissues (b), ** P < 0.01 vs. Normal group) and in CRC cell line (C, *P < 0.05 vs. FHC group); (d) RNaseR digestion was used to verify the ring structure of circ_0068464 in HCT116 and LS174T cells, ***P < 0.001 vs. Mock group; (e) FISH experiments were performed to detect the subcellular localization of circ_0068464.