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. 2022 Feb 15;13(3):5113–5125. doi: 10.1080/21655979.2022.2036905

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Effects of knockdown of circ_0068464 on malignant phenotype of colorectal cancer cells. (a) The expression of circ_0068464 in the cells in each group was detect using qRT-PCR. For HCT116 or LS174T cells, (b) MTT was utilized to measure proliferation rate; (c-e) flow cytometry was carried out to check the cycle (c) and apoptosis rate (e); (d) transwell was adopted to determine the abilities of migration; (f) Western blot was adopted to check MMP-2 and MMP-9 expression. **P < 0.01 vs. siNC group.