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. 2022 Jan 18;13(2):2840–2850. doi: 10.1080/21655979.2021.2024687

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Liquiritin reverses the proliferation of ox-LDL-induced hVSMCs. (a) An MTT assay was performed to measure the cell proliferation of ox-LDL-induced hVSMCs. (b) Caspase-3 activity of ox-LDL-induced hVSMCs was determined using the colorimetric assay kit. (c, d) The cell apoptosis rates of ox-LDL-induced hVSMCs were measured by flow cytometry (FCM) analysis. (e, f) The protein expression levels of Bcl-2 and Bax in ox-LDL-induced hVSMCs were detected by Western blot analysis and quantified by ImageJ software. **P < 0.01 vs. Control; #^, ## P < 0.05, 0.01 vs. ox-LDL group.