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. 2022 Jan 18;13(2):2840–2850. doi: 10.1080/21655979.2021.2024687

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Liquiritin increases SIRT1 expression in ox-LDL-induced hVSMCs. The mRNA expression levels of SIRT1 in ox-LDL-induced hVSMCs were detected by RT-qPCR analysis. (b) The protein expression levels of SIRT1 in ox-LDL-induced hVSMCs were detected by Western blot analysis. (c) The mRNA expression levels of SIRT1 in plaque and normal tissues of 30 coronary heart disease patients were detected by RT-qPCR analysis. (d) The protein expression levels of SIRT1 in plaque and normal tissues of two random coronary heart disease patients were detected by Western blot analysis. **P < 0.01 vs. Control; #^, ## P < 0.05, 0.01 vs. ox-LDL group; $$ P < 0.01 vs. Normal tissue.