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. 2022 Feb 3;13(2):4411–4427. doi: 10.1080/21655979.2022.2033447

Figure 4.

Figure 4.

MiR-637 functions a tumor suppressive effect on OS.a) miR-637 levels were measured within OS and corresponding non-carcinoma tissues (n = 40) by qRT-PCR. b) miR-637 level showed negative correlation with circ_UBAP2 levels within OS tissues. c) miR-637 levels within OS cells (U-2OS, MG63, SaOS-2, HOS) and healthy osteoblasts (hFOB1.19) were measured by qRT-PCR. D) miR-637 levels were measured upon co-transfection of miR-637 inhibitor (or inhibitor NC) with miR-637 mimic (or mimic NC) in OS cells through qRT-PCR. e) Ttransfected HOS cell proliferation was detected through CCK-8 assay. f) Transfected SaOS-2 cell proliferation was detected through CCK-8 assay. g) Invasion and migration of transfected HOS and SaOS-2 cells were analyzed through Transwell assays. h) Transfected HOS and SaOS-2 cell apoptosis was analyzed through flow cytometry. *P < 0.05, ** P < 0.01.