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. 2022 Feb 3;13(2):4411–4427. doi: 10.1080/21655979.2022.2033447

Figure 5.

Figure 5.

MiR-637 partially reverses the tumor-promoting effect of circ_UBAP2 on OS cells.HOS cells with stable over-expression of circ_UBAP2 were transfected with miR-637 mimic, while SaOS-2 cells with circ_UBAP2 silencing were subjected to miR-637 inhibitor transfection. a) miR-637 expression within OS cells was analyzed through qRT-PCR. b) Transfected HOS and SaOS-2 cell proliferation was detected through CCK-8 assay. c) Invasion and migration of transfected HOS and SaOS-2 cells were analyzed through Transwell assays. d) Transfected HOS and SaOS-2 cell apoptosis was analyzed through flow cytometry. *P < 0.05, **P < 0.01.