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. 2022 Feb 3;13(2):4411–4427. doi: 10.1080/21655979.2022.2033447

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Circ_UBAP2 promotes OS progression by regulating HMGB2.HOS cells with stable over-expression of circ_UBAP2 and SaOS-2 cells with circ_UBAP2 silencing were subjected to pc-HMGB2 transfection, respectively. a) HMGB2 levels within OS cells were analyzed through qRT-PCR. b) Transfected HOS and SaOS-2 cell proliferation was evaluated through CCK-8 assay. c) Transfected HOS and SaOS-2 cell invasion and migration were measured through Transwell assays. d) Transfected HOS and SaOS-2 cell apoptosis was analyzed through flow cytometry. * P < 0.05, **P < 0.01