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. 2022 Jan 22;13(2):3503–3515. doi: 10.1080/21655979.2022.2029108

Figure 1.

Figure 1.

CircPTPN12 declined in keloid tissue and keloid fibroblasts, and silencing circPTPN12 could promote the growth of keloid fibroblasts. (a) qRT-PCR was applied to detect the expression of circPTPN12 in keloid tissue. (b) qRT-PCR was applied to detect the expression of circPTPN12 in keloid fibroblasts. (c) qRT-PCR was used to detect the transfection efficiency of circPTPN12 knockdown. (d) MTT assay was applied to assess the cell viability of keloid fibroblasts. (e) Flow cytometry was used to detect cell apoptosis of keloid fibroblasts. (f) Transwell assay was applied to assess the cell migration and invasion of keloid fibroblasts. ** P < 0.01, *** P < 0.001.