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Silencing circPTPN12 targeted miR-21-5p/SMAD7 axis and activated the Wnt pathway to strengthen keloid fibroblasts’ growth. (a) The protein levels of cyclinD1 and c-myc were induced after silencing circPTPN12, while partly reversed by inhibition of miR-21-5p in keloid fibroblasts. Data were shown as mean ± SD.*** P < 0.001.
