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. 2022 Mar 7;13(3):6942–6954. doi: 10.1080/21655979.2022.2036398

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — miR-193b-3p targeted SIAH1. (A) The targeted binding sites of miR-193b-3p and SIAH1 were predicted by TargetScan; (B) The targeting relationship between mir193B-3p and SIAH1 was verified by dual-luciferase reporter assay; (C) The mRNA and protein levels of SIAH1 in brain tissue of rats in different groups were detected by RT-qPCR and WB; Measurement data were expressed as mean ± standard deviation, N = 6, one-way ANOVA was used for data comparison among groups, and Tukey’s multiple test was used for the post hoc test. P was obtained from a bilateral test, ** P < 0.01, *** P< 0.001.