Table 6.
Comparison of Liver Enzymes and Lipid Changes Based on Anti-Malaria Among Malaria-Infected Patients at Dembia Primary Hospital and Teda Health Center, North West Ethiopia, 2020
| Parameters | Types of Treatment and Mean ± SD | P-value | |||
|---|---|---|---|---|---|
| ACT | Chloroquine | ACT+Premaquine | Chloroquine+Primaquine | ||
| AST (IU/L) | 27.50±7.50 | 33.00±0.00 | 34.90±16.20 | 29.30±7.50 | 0.573 |
| ALT (IU/L) | 23.33±10.23 | 27.50±12.02 | 23.77±11.67 | 19.57±3.77 | 0.764 |
| ALP (IU/l) | 60.17±26.75 | 53.00±7.10 | 76.38±38.58 | 85.29±36.87 | 0.530 |
| HDL (mg/dl) | 39.83±15.10 | 34.50±20.50 | 24.79±11.46 | 26.43±10.52 | 0.023* |
| LDL (mg/dl) | 67.67±7.37 | 80.00±12.73 | 59.14±25.10 | 62.14±17.39 | 0.543 |
| TC (mg/dl) | 102.00±46.34 | 118.50±7.78 | 103.85±28.58 | 89.57±41.91 | 0.598 |
| TG (mg/dl) | 111.16±5387 | 119.00±69.30 | 106.48±43.38 | 71.14±32.20 | 0.214 |
Note: *Statistically significant (P<0.05) against drug type.
Abbreviations: ALT, alanine amino transferase; AST, aspartate amino transferase; ALP, alkaline phosphatase; CI, confidence interval; IU/L, international unit per liter; mg/dl, milligram per deciliter; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TC, total cholesterol; TG, triglyceride; SD, standard deviation.