Table 2.

Associations of the Slope of Energy With the Presence of MPS in this Parkinson’s Disease-Free Sample (n = 293)

	Model 1: Unadjusted	Model 2: Adjusted for Age	Model 3: Model 2 + Fatigue	Model 4: Model 3 + Baseline SEL	Model 5: Model 4 + WMH	Model 6: Model 5 + Right Striatum + Normalized Total Gray Matter Volume	Model 7: Model 6 + Disease Conditions Affecting MPS	Model 8: Model 7 + SPPB a Year 1
	Unadjusted OR (95% CI)	Adjusted OR (95% CI)
SEL slopes	2.20 (1.34, 3.63)	2.19 (1.33, 3.61)	1.98 (1.18, 3.30)	1.96 (1.18, 3.26)	2.00 (1.19, 3.37)	2.20 (1.29, 3.77)	2.26 (1.31, 3.91)	2.03 (1.16, 3.54)

Notes: MPS = mild parkinsonian signs; SEL = self-reported energy level; SPPB = Short Physical Performance Battery; WMH = white matter hyperintensities. Model 2: Model 8 adjusted for covariates that were bivariately associated with MPS (ie, age; refer to Table 1). In Model 7, diseases included the prevalence of cardiovascular disease, stroke, myocardial infarction, and diabetes. Due to small values, the slope of energy was multiplied by 10 for interpretation purposes. The sign of slope was reversed with higher values indicating a greater decline in SEL.