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. 2022 Apr 1;18(4):983–992. doi: 10.5664/jcsm.9760

Figure 1. Study flowchart.

Figure 1

Flow chart of the study protocol. Of 375 selected patients, 56 were excluded and 319 were randomized: 221 in the severe OSA trial and 98 in the nonsevere OSA trial. Of this 319, 73 were excluded because of inadequate echocardiogram. Of the remaining 246, 122 had and 124 did not have PH. Of the 122 with PH, 87 had severe OSA and 35 had nonsevere OSA who were included in the subgroup analysis, severe OSA and nonsevere OSA, respectively. Of the 124 without PH, 80 had severe OSA and 44 had nonsevere OSA who were included in the subgroup analysis, severe OSA and nonsevere OSA, respectively. Therefore, the severe OSA subgroup had 167 patients and nonsevere OSA had 79 patients. ECHO = transthoracic echocardiogram, OSA = obstructive sleep apnea, PH = pulmonary hypertension, RCT = randomized controlled trial, sPAP = systolic pulmonary artery pressure.