Table 3.
Cardiopulmonary coupling and cyclic variation of heart rate of participants by group before and after 3 months of PAP therapy.
| OSA (n = 32) | OHS (n = 11) | Baseline OSA vs OHS Comparison (P) | Between Visit OSA vs OHS Comparison (P) | |||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Post-Treatment | P | Baseline | Post-Treatment | P | |||
| SQI | 37.1 (20.2) | 56.5 (16.9) | .004 | 30.5 (17.2) | 47.0 (17.7) | .06 | .37 | .77 |
| SAI (%) | 38.7 (26.5) | 15.2 (15.3) | .002 | 51.7 (32.4) | 25.3 (15.4) | .02 | .25 | .96 |
| HFC (%) | 28.3 (23.7) | 52.3 (22.0) | .001 | 20.6 (12.1) | 38.8 (23.0) | .06 | .41 | .56 |
| LFC (%) | 53.0 (27.4) | 26.7 (12.2) | .001 | 60.4 (19.8) | 40.2 (16.1) | .03 | .48 | .47 |
| vLFC (%) | 17.0 (11.6) | 17.6 (10.7) | .50 | 17.4 (10.4) | 19.1 (8.1) | .58 | .83 | .87 |
| e-LFCBB (%) | 24.7 (21.1) | 9.2 (6.4) | .001 | 20.2 (10.0) | 15.6 (11.4) | .50 | .56 | .18 |
| e-LFCNB (%) | 11.2 (14.4) | 1.6 (2.5) | .001 | 18.1 (23.9) | 1.8 (3.8) | .04 | .54 | .67 |
| Total eLFC (%) | 35.9 (31.4) | 10.8 (7.5) | .001 | 38.3 (24.0) | 17.4 (11.2) | .05 | .98 | .59 |
| LFC/HFC ratio | 7.1 (17.4) | 1.6 (4.3) | .15 | 5.6 (6.1) | 2.4 (3.0) | 1.00 | .05 | .15 |
| CVHR (%) | 45.1 (22.2) | 26.0 (17.2) | .02 | 57.6 (33.1) | 31.4 (13.5) | .01 | .24 | .67 |
Data are presented as mean ± standard deviation or median (interquartile range) unless otherwise stated. Bold values: P < .05. CVHR = cyclic variation of heart rate, eLFC = elevated low-frequency coupling, e-LFCBB = elevated low-frequency coupling broad band, e-LFCNB = elevated low-frequency coupling narrow band, OHS = obesity hypoventilation syndrome, OSA = obstructive sleep apnea, PAP = positive airway pressure, SAI = sleep apnea indicator, SQI = sleep quality index, HFC = high-frequency coupling, LFC = low-frequency coupling, vLFC = very-low-frequency coupling.