FIG. 9.

Cortical drug content, cortical total phospholipids, urinary excretion of phospholipids, DNA specific radioactivity in renal cortex, apoptotic cells in cortex sections (TUNEL), and serum creatinine in rats treated with saline (controls) or with gentamicin (10 mg/kg), netilmicin (10 mg/kg), amikacin (40 mg/kg), or isepamicin (40 mg/kg) for 10 days. Values are means ± standard deviations (n = 6 in each group). Groups with different letters are significantly different from each other based on statistical analysis by ANOVA followed by Scheffe post hoc test (P < 0.05). prot., protein.