Table 2.
Adjusted Mean Changes in Intraocular Pressure (IOP) in Eyes Who Underwent Xen Implant with Primary Needling (Needling) and Those Who Did It Without Primary Needling (No-Needling)
| Needling (n=19) | No-Needling (n=44) | Difference | Pa | |
|---|---|---|---|---|
| MCIOPD1, mm Hg | ||||
| Mean (SE) | 8.3 (1.6) | 8.3 (1.0) | 0.0 (2.0) | 0.9909 |
| 95% CI | 5.2 to 11.4 | 6.3 to 10.3 | −4.1 to 4.1 | |
| MCIOPW1, mm Hg | ||||
| Mean (SE) | 7.1 (1.6) | 5.4 (1.0) | 1.7 (2.0) | 0.4103 |
| 95% CI | 4.0 to 10.2 | 3.4 to 7.4 | −2.4 to 5.8 | |
| MCIOPM1, mm Hg | ||||
| Mean (SE) | 3.4 (1.8) | 3.8 (11) | −0.4 (2.3) | 0.8512 |
| 95% CI | −0.2 to 6.9 | 1.6 to 6.1 | −5.1 to 4.2 | |
| MCIOPM3, mm Hg | ||||
| Mean (SE) | 4.3 (1.1) | 3.7 (0.7) | 0.6 (1.5) | 0.7057 |
| 95% CI | 2.0 to 6.6 | 2.3 to 5.1 | −2.5 to 3.6 | |
| MCIOPM6, mm Hg | ||||
| Mean (SE) | 4.3 (1.2) | 3.7 (0.7) | 0.6 (1.5) | 0.6866 |
| 95% CI | 2.0 to 6.6 | 2.2 to 5.1 | −2.5 to 3.7 | |
| MCIOPM12, mm Hg | ||||
| Mean (SE) | 4.9 (0.7) | 4.9 (0.4) | 0.0 (0.9) | 0.9691 |
| 95% CI | 3.5 to 6.2 | 4.0 to 5.8 | −1.9 to 1.8 |
Notes: aAnalysis of covariance (ANCOVA). The model included “Primary needing” as a factor and age, preoperative IOP and number of ocular hypotensive medications, type of glaucoma, mitomycin-C dose, type of surgery (XEN alone or XEN + phacoemulsification), mean defect, and reason for performing surgery as covariates.
Abbreviations: MCIOP, mean change in intraocular pressure; SE, standard error; CI, confidence interval; D, day; W, week; M, month.