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Main results of a recent Cochrane Review on the clinical management of patients with NP and CR with biologics.
| mAb compared to placebo | Disease-specific HRQL | Disease severity | Serious adverse events |
|---|---|---|---|
| Dupilumab (anti IL-4) | Improve | Results in a reduction | May result in a reduction in number |
| Mepolizumab (anti IL-5) | May improve | Very uncertain difference | Very uncertain difference |
| Omalizumab (antiIgE) | Probably improve | No evidence | Very uncertain difference |
