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. 2022 Feb 28;3:840454. doi: 10.3389/falgy.2022.840454

Table 2.

Panel of galectin (Gal) inhibitors used in this study.

Name Structure Targets* Kd (μM) References
Lactose graphic file with name falgy-03-840454-i0026.jpg Gal-1 330 (12)
Gal-2 85 (13)
Gal-3 26-1000 (13)
Gal-8 150 (14)
Gal-9 N.A. (15)
Gal-12 N.A. (16)
TDG graphic file with name falgy-03-840454-i0027.jpg Gal-1 24 (17)
Gal-2 340
Gal-3 49
Gal-8 61
Gal-9 38
TD 139 graphic file with name falgy-03-840454-i0028.jpg Gal-1 0.012 (17)
Gal-2 >5
Gal-3 0.014
Gal-8 86
Gal-9 0.68
GB 1107 graphic file with name falgy-03-840454-i0029.jpg Gal-1 3.7 (18)
Gal-2 0.64
Gal-3 0.037
Gal-8 83
Gal-9 2.4
G3-C12 Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr- Gal-3 0.088 (19)
Thr-His-Asp-Cys-Pro-Val-Lys-Arg
*,

Targets involved galectins expressed by immune cells.

N.A., not available.