TABLE 3.

Maximum decrease in plasma cytokine and lactate concentrations in treatment groups after admission

Parameter	Placebo		Lexipafant
	No. of patients	Median (range) % decrease in concn	No. of patients	Median (range) % decrease in concn
Lactate	58	27.6 (0–86.2)	59	36.4 (0–85.5)
IL-6	59	69.1 (0–100)	62	67.8 (0–100)
IL-8	59	45.9 (0–99.8)	62	45.3 (0–98.5)
TNF-α	59	33.1 (0–96.4)	62	13.3 (0–98.5)
TNF-RI	58	21.7 (0–79.9)	62	17.8 (0–90.1)
TNF-RII	58	15.8 (0–92.3)	62	8.6 (0–83.6)