Fig. 3.

Representative gross and histology images.

A CT-scan of a COVID-19 pneumonia after single vaccination. B Macroscopic image; formalin-fixed; lung parenchyma is widely destroyed with dark areas of hemorrhage and loss of spongious morphology. C H&E 40x magnification; acute DAD with prominent hyaline membranes. D H&E 200x magnification; organizing DAD with fibroblastic proliferation and loss of alveolar spaces. E RNA-ISH 100x magnification; high viral infection of pneumocytes and probably macrophages around emphysematic alveolar structures (F) higher magnification of the area in E marked by a square. G H&E 400x magnification; acute bacterial pneumonia with dense aggregates of granulocytes within the alveolar spaces. H Grocott 200x magnification; Invasive aspergillosis of the lung. I) RNA-ISH 300x magnification; infection of three histiocytic cells (arrow heads) within the adventitia of the aorta, insert: higher magnification of the positive cell within the dashed square.