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. 2021 Mar 29;225(7):1162–1167. doi: 10.1093/infdis/jiab095

Table 1.

Demographic Characteristics of Study Cohort

Characteristic Women, No. (%)a P Value
HIV Uninfected (n = 95) HIV Infected (n = 111)
Baseline maternal
 Age, mean (SD) y 25 (5) 30 (6) <.001
 Married 76 (80.0) 98 (88.3) .10
 Employed 21 (22.1) 42 (37.8) .01
 Educational level
  No formal education 3 (3.2) 3 (2.7) .54
  Less than college 81 (85.3) 100 (90.1)
  College 11 (11.6) 8 (7.2)
 Nonsmoker during pregnancy 95 (100) 111 (100.0)
 No alcohol use during pregnancy 92 (96.8) 95 (85.5) .005
 BMI, mean (SD)b 24.77 (4.19) 24.81 (4.10) .92
Obstetric
 GA, mean (SD), wk 19 (3) 20 (4) .04
 Parity, mean (SD) 1 (1) 2 (2) <.001
Immune status
 Previous tuberculosis diagnosis 1 (1.1) 5 (4.5) .22
 CD4+ T-cell count, mean (SD), cells/µL 807 (1735) 405 ( 205) <.001
 Baseline immune activation, mean (SD), %c 26.2 (13.0) 39.6 (18.8) <.001

Abbreviations: BMI, body mass index; cART, combination antiretroviral therapy; GA, gestational age; HIV, human immunodeficiency virus; SD, standard deviation.

aData represent no. (%) of women unless otherwise specified.

bBMI is calculated as weight in kilograms divided by height in meters squared.

cImmune activation is expressed as the percentage of CD8+CD3+ T cells expressing CD38 and HLA-DR.