Table 1.
Demographic Characteristics of Study Cohort
Characteristic | Women, No. (%)a | P Value | |
---|---|---|---|
HIV Uninfected (n = 95) | HIV Infected (n = 111) | ||
Baseline maternal | |||
Age, mean (SD) y | 25 (5) | 30 (6) | <.001 |
Married | 76 (80.0) | 98 (88.3) | .10 |
Employed | 21 (22.1) | 42 (37.8) | .01 |
Educational level | |||
No formal education | 3 (3.2) | 3 (2.7) | .54 |
Less than college | 81 (85.3) | 100 (90.1) | |
College | 11 (11.6) | 8 (7.2) | |
Nonsmoker during pregnancy | 95 (100) | 111 (100.0) | |
No alcohol use during pregnancy | 92 (96.8) | 95 (85.5) | .005 |
BMI, mean (SD)b | 24.77 (4.19) | 24.81 (4.10) | .92 |
Obstetric | |||
GA, mean (SD), wk | 19 (3) | 20 (4) | .04 |
Parity, mean (SD) | 1 (1) | 2 (2) | <.001 |
Immune status | |||
Previous tuberculosis diagnosis | 1 (1.1) | 5 (4.5) | .22 |
CD4+ T-cell count, mean (SD), cells/µL | 807 (1735) | 405 ( 205) | <.001 |
Baseline immune activation, mean (SD), %c | 26.2 (13.0) | 39.6 (18.8) | <.001 |
Abbreviations: BMI, body mass index; cART, combination antiretroviral therapy; GA, gestational age; HIV, human immunodeficiency virus; SD, standard deviation.
aData represent no. (%) of women unless otherwise specified.
bBMI is calculated as weight in kilograms divided by height in meters squared.
cImmune activation is expressed as the percentage of CD8+CD3+ T cells expressing CD38 and HLA-DR.