Table 2.

Hypothesis driven (sub-)cortical volume model 2.

Brain region	Psychopathology symptoms	B	S.E.	p -value
Anterior cingulate	Internalizing	–0.271	0.085	1.39e-03*
	Externalizing	–0.351	0.085	3.61e-05*
	Dysregulation Profile	–0.566	0.118	1.71e-06*
Orbitofrontal	Internalizing	–0.087	0.083	2.92e-01
	Externalizing	-0.248	0.083	2.91e-03*
	Dysregulation Profile	–0.364	0.114	1.42e-03*
Rostral middle frontal	Internalizing	–0.18	0.084	3.28e-02
	Externalizing	–0.265	0.084	1.73e-03*
	Dysregulation Profile	–0.467	0.116	6.03e-05*
Amygdala	Internalizing	–0.152	0.078	5.19e-02
	Externalizing	–0.323	0.078	3.92e-05*
	Dysregulation Profile	–0.374	0.107	5.05e-04*
Hippocampus	Internalizing	–0.012	0.083	8.81e-01
	Externalizing	–0.048	0.084	5.62e-01
	Dysregulation Profile	–0.28	0.116	1.6e-02*
Striatum	Internalizing	–0.163	0.085	5.57e-02
	Externalizing	–0.134	0.086	1.18e-01
	Dysregulation Profile	–0.301	0.119	1.16e-02*

^*Indicates significance after correction for multiple testing using FDR-BH at a q-value of 0.05.