Table 3.
Associations of AKI and initiation of KRT with receipt of a palliative care consult
| Covariates | Odds of Receiving a Palliative Care Consult, n=4276a | ||
|---|---|---|---|
| Unadjusted Odds Ratio (95% Confidence Interval) | Adjusted Odds Ratio (95% Confidence Interval) | P Value | |
| AKI | |||
| No AKI | 1 | 1 | Reference |
| AKI, no KRT | 7.39 (6.16 to 8.90) | 1.81 (1.40 to 2.33) | <0.001 |
| AKI with KRT | 24.65 (17.92 to 34.22) | 2.45 (1.52 to 3.97) | <0.001 |
| Age, 10 yr | 1.47 (1.40 to 1.55) | 1.71 (1.56 to 1.88) | <0.001 |
| Sex | |||
| Women | 1 | 1 | Reference |
| Men | 1.09 (0.93 to 1.28) | 0.66 (0.53 to 0.81) | <0.001 |
| Race | |||
| White | 1 | 1 | Reference |
| Black | 0.70 (0.55 to 0.89) | 0.97 (0.72 to 1.30) | 0.82 |
| Asian | 0.91 (0.67 to 1.22) | 0.87 (0.59 to 1.27) | 0.48 |
| Other/multiracial | 0.68 (0.56 to 0.82) | 1.13 (0.83 to 1.54) | 0.44 |
| Pacific Islander/Native American | 0.45 (0.11 to 1.29) | 2.24 (0.47 to 7.92) | 0.25 |
| Ethnicity | |||
| Hispanic | 1 | 1 | Reference |
| Non-Hispanic | 1.67 (1.39 to 2.02) | 1.36 (0.99 to 1.87) | 0.06 |
| Cirrhosis | 1.20 (0.65 to 2.07) | 1.12 (0.53 to 2.22) | 0.76 |
| Cancer | 2.21 (1.80 to 2.70) | 2.03 (1.58 to 2.60) | <0.001 |
| Body mass index, 5 kg/m2 | 0.92 (0.87 to 0.97) | 1.01 (0.94 to 1.09) | 0.76 |
| eGFR, 15 ml/min per 1.73 m2 | 0.76 (0.73 to 0.79) | 1.02 (0.96 to 1.09) | 0.79 |
| mSOFA maximum value | 1.32 (1.30 to 1.35) | 1.17 (1.12 to 1.23) | <0.001 |
| ICU admission | 8.03 (6.77 to 9.54) | 1.55 (1.10 to 2.16) | 0.010 |
| Mechanical ventilation | 9.77 (8.19 to 11.67) | 1.24 (0.83 to 1.86) | 0.30 |
| CPR/rapid response | 6.37 (5.33 to 7.61) | 1.50 (1.18 to 1.90) | 0.001 |
| Length of stay, d | 1.05 (1.05 to 1.06) | 1.02 (1.02 to 1.03) | <0.001 |
The adjusted odds ratios and P values were calculated using AKI group and adjusting for age, sex, race, ethnicity, body mass index, eGFR, mSOFA score, comorbidities (cirrhosis and cancer), and health care utilization (ICU admission, mechanical ventilation, CPR/rapid response, and length of stay). mSOFA, modified sequential organ failure assessment; ICU, intensive care unit; CPR, cardiopulmonary resuscitation.
Multivariable imputation by chained equations was used to fill in missing data for race, ethnicity, body mass index, eGFR, and mSOFA.