FIG. 2.

Effects of atovaquone on the cellular ATP contents of P. carinii f. sp. carinii populations in vitro, expressed as percent inhibition compared to ATP levels in untreated controls. Bars represent the averages of 12 separate experiments using P. carinii isolated from different individual rats ± standard errors of the means. The three concentrations of atovaquone tested and expressed as 0.1 to 10.0 μg are equivalent to 0.27, 2.72, and 27.2 μM, respectively.