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. 2022 Mar 18;13:850993. doi: 10.3389/fimmu.2022.850993

Table 3.

The top 5 hub genes.

Genes Description Degree MCC MNC Sterss Log2FC Expression change
IL1B Interleukin 1 beta 10 38 10 78 3.43222906 Upregulated
TNF Tumor necrosis factor 12 37 11 130 1.26641463 Upregulated
IRF1 Interferon regulatory factor 1 8 26 8 48 1.17112479 Upregulated
HMGB1 High mobility group box 1 5 18 5 20 -1.01820995 Downregulated
P2RX7 Purinergic receptor P2X 7 4 12 4 10 -1.25950113 Downregulated

MCC, maximal clique centrality; MNC, maximum neighborhood component.