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Serum concentration-time profile of SCH 56592 in dogs during and following daily p.o. administration of 40 mg of SCH 56592 per kg as a suspension in MC for eight consecutive days. Sampling times were at 1, 4, 6, and 8 h on the first day of dosing (day 1), predose on days 2, 6, and 7, and at 0.5, 1, 2, 4, 6, 8, 12, 24, 48, 72, 96, and 120 h after the last dose (administered on day 8). Each vertical bar represents 1 standard deviation from the mean.
