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. 2021 Jul 1;32(7):548–559. doi: 10.5152/tjg.2021.19747

Figure 3.

Figure 3.

Representative photomicrographs exhibiting histopathological, histochemical, and immunohistochemical changes of the ischemic colon mucosa in the ischemia groups. (A) Massive destruction, tissue necrosis and submucosal neutrophil infiltration in colon mucosa. H&E ×40. (B) Massive mucin loss in ischemic colon mucosa is seen with Alcian blue method (positive cytoplasms are noted with arrows). Alcian blue ×40. (C) Decreased PCNA expression in ischemic colon epithelial cells (positive staining is noted with arrows). PCNA ×40. (D) Increased HIF-1α expression in ischemic colon epithelial cells (positive staining is noted with arrows). HIF-1α ×40. (E) Increased TUNEL expression in ischemic colon epithelial cells (positive staining is noted with arrows). TUNEL ×40.