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. 2022 Apr 2;121(9):1619–1631. doi: 10.1016/j.bpj.2022.04.003

Figure 3.

Figure 3

Snapshots of the spread of infected epithelial cells (yellow, infected in eclipse phase; red, infected and shedding) from a single infected cell, post eclipse phase, shedding 2 K infectious progeny per day. Rows denote 12, 24, and 36 h. Columns denote nasal passage, trachea (generation (Gen) 0), Gen 5, Gen 10, and Gen 15. Note that the horizontal and vertical scales for each column, depicted in row 3, are specific to each generation (Table S1). Further noted in row 3, the length of Gen 10 (5.56 mm) includes a small portion of Gen 11 due to virions diffusing and infecting against a weak mucus advection, with a gray line marking the boundary between Gen 10 and 11, and a more pronounced effect against even weaker mucus advection in Gen 15 (1.68 mm long), with almost half of infection in Gen 16.