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The pharmacokinetic parameters of in vivo pharmacokinetic study.
| Pharmacokinetic parameters | Passive group | Ionto group |
|---|---|---|
| C max (ng/mL) | 38.16 ± 9 | 73.56 ± 6 |
| T max (min) | 90 | 60 |
| AUC0-T (min ng/mL) | 4890.15 | 9791.75 |
| AUMC0-Inf (min min ng/mL) | 832989.71 | 1444123.57 |
| Ke 1/min | 0.0102 | 0.0103 |
| Cl (mg)/(ng mL/min) | 0.000707 | 0.000362 |
| MRT0-T (min) | 147.41 | 130.80 |
| ER in vivo | — | 2.88 |
